I would be interested to see how he does in the NFL.
To me his offense is a gimmick. It relies on hurrying so that the offense has matchup advantages. It uses a lot of shotgun draws, sweeps and other plays that generally don't work against good defenses - ie Stanford, AU (a good line at least), LSU, etc. I think NFL defensive coordinators would have no problem adjusting.
At any level players make up the largest component of success. In the NFL that's true but there the QB is even more important than any other position. The difference in winning and losing is much smaller in the NFL as well. Maybe he can succeed, but I dunno. The idea that his offense will revolutionize the nfl is laughable.