Meh, I'll quibble a bit with this. tOSU, Illinois, Northwestern and Indiana run pure spread offenses, and several more Big Ten schools spend a considerable portion of their offensive snaps in single-back, three-and-four receiver looks (Nebraska, Minnesota, Purdue, Penn State, Maryland). I'd argue that the only pure pro-set teams in the B1G these days are Rutgers, Wisconsin, Michigan State and Iowa.
Honestly, most of the country is moving in this direction. In 2014, the SEC has eight teams (over half the conference) that run a pure spread offense, and several more that use a lot of spread looks - Alabama included.