I seriously doubt it. 5 of the scripts plays are targeted to Cooper. (Cooper said it the other day) and honestly, it's a scripted plays... It's how we execute those plays. OSU might zero on Cooper too much and That leaves Jones and White and Howard to open up and that's not good for OSU Defense.
I have heard that Kiffin scripts his first 10-15 plays. I am not sure how we will cover Cooper, but if we play the same defense that we did against MSU, you might struggle early on.
When we played MSU, we played man vs their best WR and corners behind that. It opened up the middle of the field and MSU killed us on the ground - but we shut down their passing game.
If you come out with a game plan that relies too heavily on Cooper during those scripted plays, it could cost you a few possessions until you adapt.