I was surprised they were calling it "Norco." I thought everyone just used the generic "hydrocodone," instead of Norco or Lortab. I've actually been off and on it many times with orthopedic surgeries. I have several bottles stuck back at any given time. The main reason, is that I have a mutation in the enzyme CYP450-2C19 which metabolizes many drugs, codeine, for one and hydrocodone is a close analog. You don't tend to take much of a drug is if just doesn't do much for you. Some drugs, I'm an ultra-fast metabolizer of, Vallium for example. With Nexium, the statement was "It is doubtful this subject can attain a therapeutic level...