OM is still the better "team" (injuries notwithstanding and I haven't kept up) offensively IMO, I don't know that the who's can stop them or score enough points.
As for the who's - all you have to do is stop their run game. Task is simpler for OM's D; if they can halfway do it, I still think they will win.
But this is also a big rivalry game, so who knows....