Probably don't run em as often, because the Defense lines up to come after our Running backs. Since we don't have a Fullback to block and lead the way, a RB is a smaller blocker.
In the heyday of the Wishbone attack we ran that type play a lot, but again we had some really great linemen. We could tell them we were gonna run the ball their way, and generally they couldn't stop us.
Now we run the RPO. Different formations, but the Run Pass is nearly always there as an option.
The RPO is currently ahead of many Defenses. When we ran the Bone, we had some good receivers, but nothing like today. Today, running the RPO, we can get large chunks of yardage on any given play.