It was very telling that he said in that interview that he had never played in a system in which he has to identify the Mike and adjust protections. Many college offenses, and almost every NFL offense, has the QB doing this because the center is not standing up and cannot see what is happening well enough to do so once he settles over the ball.
IMO, if he has never been asked to do so it is because he was never trusted to diagnose it properly. Now, that does not make him a poor QB. Tua also struggled doing this at Alabama and continues to struggle doing it at Miami. But the great QBs have a much higher understanding of what is happening on the other side of the ball. They are as successful as they are because they recognize what the defense is going to do, and they have a plan to deal with that BEFORE THE BALL IS SNAPPED.
Guys like Cam are very talented physically, but need a lot more help with the rest of the game. And some are smart enough to do it but just don't work on it hard enough, while others just don't have the intelligence to do it. I have no idea where Cam sits in that spectrum.