At the upper end, I'd suggest Bottega (Italian), Automatic Seafood (seafood, obviously), and Blueprint on 3rd (American fusion). I would say Highlands, but it's almost impossible to get a table, even for locals.
Helen (high end southern comfort food), and El Barrio (nice Mexican) on 2nd Avenue North are also very good.
All except El Barrio are hard to get a table, so if you want to go that direction, call now.
At a significantly lower price point, Slice Pizza in Lakeview is excellent -- not exactly traditional, but excellent.
Bogue's, a couple of blocks from the Lakeview area is a great meat-and-three. The sweet rolls will rot your teeth, but you'll buy your dentures with a smile at the memory.