I've asked this question before and haven't seen an answer better than the OL is horrible at run blocking. Whether that's due to mis-evaluated personnel, lack of development, or poor coaching, I don't know.
As others have posted: At this point in the season, we are what we are and just need to do our best to scheme around the weakness.
I do think the lack of a credible running threat will cost us at least one game. Might be OU. Might be the barn. IF (two big letters) we make it past them, it'll be in the playoff.
If a top-flight D can just disregard the threat of the run, it drastically reduces time to pass and shrinks throwing windows. You can be one-dimensional and still beat an inferior team. If you're playing another quality team for something worth winning, it doesn't work that way.